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- The Solution
Dermadry is an FDA-cleared home-use tap water iontophoresis machine. This technology works by directing a mild current through the skin, effectively neutralizing the connection between the nerves and the sweat glands. In nearly all cases, this effectively treats excessive sweating!

Scientific Evidence

A lot of research has been conducted on the effectiveness of tap water iontophoresis in the treatment of hyperhidrosis.

The following clinical studies were performed on patients aged 8-71 years old with primary focal hyperhidrosis (mild, moderate, and severe). These clinical studies evaluated the efficiency of iontophoresis in both in clinical conditions (performed by healthcare professionals in a medical facility) and at home (patients were provided with devices and performed treatments on their own). The treatment parameters were similar in regards to the current strength, treatment duration, and treatment frequency.

Here’s a look at their findings:
  • Tap water iontophoresis treatments improve the patient’s quality of life significantly during treatment.6
  • 92.9% of patients saw results after two weeks of iontophoresis treatments.7
  • 88.9% of patients had positive results,and a majority of the patients found the maintenance program compatible with their lifestyle.8
  • Quality of life improved in 78.6% of patients after 2 weeks.9
  • Tap water iontophoresis is a simple, safe and effective therapeutic option for palmoplantar hyperhidrosis.10
  • Tap water iontophoresis is a safe and effective treatment for both palmoplantar (hands and feet) hyperhidrosis and axillary (underarms) hyperhidrosis in the pediatric population, with minimal side effects.11
  • Tap water iontophoresis is an effective method of treatment for primary palmoplantar (hands and feet) and axillary (underarms) hyperhidrosis in pediatric patients.12
  • The study demonstrates that tap water iontophoresis controls palmar (hands) hyperhidrosis after a total of eight treatments.13
  • Iontophoresis treatment is safe, effective, and easy to use for the treatment of palmar and plantar hyperhidrosis. This technique should be offered to patients with palmoplantar hyperhidrosis prior to surgical intervention or toxin injection.14
  • Tap water iontophoresis suppresses palmar hyperhidrosis. When instructions are followed, tap water iontophoresis is safe for unsupervised treatment of hyperhidrosis. Iontophoresis is a simple, economic and effective therapy that should be offered to patients for control of palmar hyperhidrosis prior to surgical intervention. Iontophoresis is also a suitable alternative to long-term drug therapy. The study demonstrated a success rate of 83.3%.15
  • At present, tap water iontophoresis represents the most effective therapy in hyperhidrosis of palms or soles. Patients with extremely high sweat rates respond to the treatment, no adverse effects were noticed during long-term maintenance treatment, and tap water iontophoresis not only curbs sweating, but also abates other uncomfortable symptoms, such as lividity, edema and clamminess of palms and soles.16
  • We found the treatment to be so effective in axillary (underarms) hyperhidrosis that we would recommend iontophoresisin preference to surgical excision of the sweat-glands.17
  • In our view, tap water iontophoresis is by far more successful in treating hyperhidrosis of palms and soles. In a group of 7 patients, complete relief from excessive sweating was achieved and no treatment failure was observed.18
  • Since 1968, tap water iontophoresis has been employed as the method of choice for treating palmoplantar hyperhidrosis.19
  • In 2014, an FDA panel reviewing scientific data on the matter concluded that “all 8 studies reported that tap water iontophoresis effectively reduced sweating in the majority of subjects treated with [tap water iontophoresis]”.20
Show full bibliography ...
1 Doolittle, James, Patricia Walker, Thomas Mills, and Jane Thurston. "Hyperhidrosis: an update on prevalence and severity in the United States." Archives of dermatological research 308, no. 10 (2016): 743-749.
2 Kim, Do Hun, Tae Han Kim, Seung Ho Lee, and Ai Young Lee. “Treatment of Palmar Hyperhidrosis with Tap Water Iontophoresis: A Randomized, Sham-Controlled, Single-Blind, and Parallel-Designed Clinical Trial.” Annals of dermatology29, no. 6 (2017): 728-734.
3 Elkhyat A and Agache P. Treatment of hyperhidrosis by iontophoresis of weakly mineralised water. 1993. Cutaneous Biophysics Laboratory, Department of Functional Dermatology, 25030 Besancon, France.
4 Hölzle, E., M. Pauli, and O. Braun-Falco. “Leitungswasser-Iontophorese zur Behandlung von Hyperhidrosis manuum et pedum.” Der Hautarzt 35, no. 3 (1984): 142-147.
5 Stolman, Lewis P. "Hyperhidrosis: medical and surgical treatment." Eplasty 8 (2008).
6 Akbar, Talat Masood, Mahmood A. Saqib, Sundas Fahim, Mohammad Nasir, and Haroon Nabi. "Efficacy and safety of tap water iontophoresis for palmoplantar hyperhidrosis." Journal of Pakistan Association of Dermatology 23, no. 3 (2016): 304-309.
7 Kim, Do Hun, Tae Han Kim, Seung Ho Lee, and Ai Young Lee. "Treatment of Palmar Hyperhidrosis with Tap Water Iontophoresis: A Randomized, Sham-Controlled, Single-Blind, and Parallel-Designed Clinical Trial." Annals of dermatology29, no. 6 (2017): 728-734.
8 Maj, NS WALIA, BS RATHORE Lt Col, and AK JAISWAL Col. "TREATMENT OF PALMOPLANTER HYPERHIDROSIS BY IONTOPHORESIS." Medical Journal Armed Forces India 56, no. 1 (2000): 27-28.
9 Kim, Do Hun, Tae Han Kim, Seung Ho Lee, and Ai Young Lee. "Treatment of Palmar Hyperhidrosis with Tap Water Iontophoresis: A Randomized, Sham-Controlled, Single-Blind, and Parallel-Designed Clinical Trial." Annals of dermatology 29, no. 6 (2017): 728-734.
10 Yardi, S. S., U. S. Khopkar, V. A. Phadke, and S. S. Idgunji. "Tap water iontophoresis for palmoplantar hyperhidrosis." Indian Journal of Dermatology 42, no. 3 (1997): 164-167.
11 Dagash, Haitham, Sinead McCaffrey, Katie Mellor, Agnes Roycroft, and Ingrid Helbling. "Tap water iontophoresis in the treatment of pediatric hyperhidrosis." Journal of pediatric surgery 52, no. 2 (2017): 309-312.
12 Dogruk Kacar, Seval, Pinar Ozuguz, Selma Eroglu, Serap Polat, and Semsettin Karaca. "Treatment of primary hyperhidrosis with tap water iontophoresis in paediatric patients: a retrospective analysis." Cutaneous and ocular toxicology 33, no. 4 (2014): 313-316.
13 Karakoç, Yunus, Ertuğrul H. Aydemir, M. Tunaya Kalkan, and Gaye Ünal. "Safe control of palmoplantar hyperhidrosis with direct electrical current." International journal of dermatology41, no. 9 (2002): 602-605.
14 Safe control of palmoplantar hyperhidrosis with direct electrical current. Karakoç Y, Aydemir EH, Kalkan MT, Unal G. Int J Dermatol. 2002 Sep
15 Stolman, Lewis P. "Treatment of excess sweating of the palms by iontophoresis." Archives of dermatology 123, no. 7 (1987): 893-896.
16 Hölzle, E., and N. Alberti. "Long-term efficacy and side effects of tap water iontophoresis of palmoplantar hyperhidrosis–the usefulness of home therapy." Dermatology 175, no. 3 (1987): 126-135.
17 Midtgaard, K. "A new device for the treatment of hyperhidrosis by iontophoresis." British Journal of Dermatology 114, no. 4 (1986): 485-488.
18 Hölzle, E., and T. Ruzicka. "Treatment of hyperhidrosis by a battery-operated iontophoretic device." Dermatology 172, no. 1 (1986): 41-47.
19 Hölzle, E. "Leitungswasseriontophorese." Der Hautarzt 63, no. 6 (2012): 462-468.
20 U.S. Food and Drug Administration. "Reclassification of Iontophoresis Devices Intended for Any Other Purposes." Office of the Federal Register (accessed September 1, 2018).


Some key points about iontophoresis treatment:

Why choose Dermadry?

Dermadry’s iontophoresis machine is a non-invasive, drug-free, and needle-free treatment option that effectively treats excessive sweating. Dermadry is a trusted solution, as showcased on the non-profit organization the International Hyperhidrosis Society's website.

We offer a solution for people who suffer from excessive sweating of the hands, feet also known as palmar, plantar, and axillary hyperhidrosis. Our products are tailored to meet specific customer needs, whether an individual sweats only from their hands and feet, only from their underarms or from all three areas.

Dermadry's iontophoresis device distinguishes itself through its affordability, intuitive use, and its cutting-edge technology. We are the only tap water iontophoresis machine that has received a medical device license from Health Canada.

Watch how easy it is to set up and use Dermadry!

Is Dermadry right for me?

Intended Use: Dermadry is a home-use tap water iontophoresis device designed for single patient use. It is indicated for the treatment of moderate to severe palmar, plantar, and axillary hyperhidrosis by those 13 years and older.

Please refer to the contraindications listed below to know if Dermadry is right for you.


In Canada, tap water iontophoresis machines are a Class II medical device.


DO NOT use this device if you have any of the following conditions:

NOTE: If in doubt, please contact your health professional.

Side effects

You may experience the following temporary side effects:
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